
Photo obtained from the City of Hope website
On December 1st, Orange County’s first cancer specialty hospital opened in Irvine. The 174,000-square-foot City of Hope medical facility is located at 16300 Sand Canyon Parkway.
More than 100 physician-scientists have been brought in to focus solely on treating and curing cancer. The 73-bed hospital provides access to a number of cancer-focused clinical trials, including early-stage clinical trials that require close supervision in a hospital setting.
The first floor includes an eight-bed evaluation and treatment center — essentially an urgent care that will be open around-the-clock, 365 days a year, for patients who have any issue related to their cancer.
The new hospital is part of a 72-acre academic research campus that connects the hospital to an adjacent outpatient center, which opened last year, at City of Hope’s $1 billion Irvine campus being developed at Barranca and Alton.
The facility was designed to be consistent with the principles of feng shui, with hospital rooms and corridors featuring sweeping views of nature, calming art, natural light, and no numbering on the fourth floor. (In many Asian cultures, the number four symbolizes death.)
There are also family suites that offer additional space for loved ones to stay while they support patients hospitalized for extended treatment. The suites include their own connected rooms, dining areas, and private bathrooms.
At the grand opening ceremony, Mayor Larry Agran said: “City of Hope’s presence in Irvine has sparked a wave of healthcare development across the region, creating jobs and attracting top-tier talent. But most importantly, this new hospital has the potential of providing improved outcomes for patients facing cancer and renewed hope for their loved ones.”
To learn more about the new hospital, click here.
- Orange County’s First Cancer Specialty Hospital Opens in Irvine - December 4, 2025
- Irvine Community Comes Together for Operation “Bridge the Gap” - December 2, 2025
- Mayor Agran Holds Public Hearing on E-Bike Safety Concerns - December 1, 2025

